HoLEP (Holmium Laser Enucleation of the Prostate)
Urology
Starting from
$3,500
Up to $9,500 depending on centre
Typical duration
4–8 days
Including pre-operative work-up
Content reviewed for medical accuracy by: Dr. Rodina Ainasoa · Medical Content Writer & Health Communications
Overview
HoLEP (Holmium Laser Enucleation of the Prostate) is the only size-independent surgical option for benign prostatic hyperplasia — using a holmium laser to enucleate the entire obstructive prostate tissue regardless of gland size, then morcellating it for removal. Unlike UroLift or Rezūm, which are reserved for smaller-to-moderate prostates, HoLEP delivers TURP-equivalent or superior long-term durability with less bleeding and a shorter catheterization time, making it the preferred choice for very large prostates that would otherwise require open surgery.
Your case is matched to a centre on the basis of clinical outcome data, not marketing. We coordinate every step — from pre-operative work-up to post-treatment follow-up — with a dedicated care coordinator.
What's included
HoLEP (Holmium Laser Enucleation of the Prostate)
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Key insights at a glance
Starting from
$3,500
Up to $9,500 depending on centre
Typical duration
4–8 days
Including pre-operative work-up
Procedures
2
Hold to see procedures
Partner hospitals
0
Vetted for outcome data & accreditation
HoLEP vs. TURP (Standard BPH Surgery)
Both HoLEP and TURP are highly effective surgical treatments for benign prostatic hyperplasia, but they differ in how they handle prostate size, bleeding risk, and surgeon availability. This comparison reflects current AUA (American Urological Association) guideline summaries and peer-reviewed urology literature.
| Factor | HoLEP | TURP |
|---|---|---|
| Prostate size limit | Size-independent — the only AUA guideline-endorsed option for any prostate size, including very large glands (80–150+ mL). | Best suited to prostates under roughly 60–80 mL; larger glands become technically harder and bloodier to resect. |
| Bleeding risk | Lower — the holmium laser seals blood vessels as it cuts, reducing intra- and post-operative bleeding. | Higher — resection leaves raw tissue surfaces that continue oozing, especially in larger prostates. |
| Suitability for patients on blood thinners | Considered a preferred option, per AUA guidance, for patients at higher bleeding risk, including those on anticoagulants. | Blood-thinning medication typically must be stopped before surgery due to higher bleeding risk. |
| Catheterization time | Generally shorter (often 1–2 days) due to reduced post-operative bleeding and clot risk. | Typically longer than HoLEP, particularly in larger prostates. |
| Surgeon training required | Longer learning curve — requires a fellowship-trained laser urology surgeon experienced in enucleation and morcellation technique. | Widely taught and practiced; broader surgeon availability at most urology centers. |
Source: American Urological Association (AUA) guideline summaries; NCBI/StatPearls; peer-reviewed urology literature (reviewed Sept 2026). This comparison is educational; your urologist will assess your prostate volume, medication history, and overall health to recommend the most appropriate procedure.
Global cost comparison — HoLEP (Holmium Laser Enucleation of the Prostate)
Average coordinated costs across our partner centres. Final pricing depends on clinical complexity and chosen hospital.
| Country | Avg. cost | vs. cheapest |
|---|---|---|
🇮🇳 India New Delhi · Chennai · Bengaluru · Hyderabad · Mumbai · Kochi | $3,800 | —chevron_right |
🇹🇷 Turkey Istanbul | $6,500 | +71%chevron_right |
Costs are indicative estimates and vary by procedure specifics, hospital, and clinical complexity. Request a personalised estimate for your specific case.
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Frequently asked questions
HoLEP, TURP, and Rezūm are all effective, but they differ in scope and durability. TURP is the traditional gold standard but is best suited to prostates under roughly 60–80 mL, since larger glands become technically harder and bloodier to resect. HoLEP uses a holmium laser to enucleate the entire obstructive adenoma regardless of prostate size — it is the only procedure endorsed by AUA guidelines as size-independent, making it the preferred option for very large prostates (80–150+ mL) that would otherwise need open surgery. Rezūm (water vapor therapy) is minimally invasive and preserves sexual function well, but it is reserved for smaller-to-moderate prostates and offers less durable symptom relief than HoLEP or TURP. For patients on blood thinners, HoLEP's laser sealing of tissue as it cuts also means significantly less bleeding than TURP.
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Clear, transparent guidance
CureSureMedico charges a transparent, fixed coordination fee to the patient or institutional payer. Treatment costs are billed directly by the partner hospital.